Opportunity Information: Apply for CDC RFA PS19 1905
The CDC, through the National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (NCHHSTP), offered this cooperative agreement funding opportunity (CDC RFA PS19-1905) to strengthen the use of epidemiologic and economic modeling to guide real-world public health decisions. The core purpose is to develop and apply scientifically sound disease transmission and cost-effectiveness models that can help public health leaders understand what interventions are likely to prevent the most infections, reduce illness, and make the best use of limited resources. In practical terms, the opportunity is about turning surveillance data, program data, and research evidence into forward-looking projections and economic comparisons that can inform which strategies should be implemented, scaled, or prioritized.
The modeling focus spans several interconnected program areas: HIV, viral hepatitis, sexually transmitted diseases, and tuberculosis, and it also references school health as part of the broader prevention context. The CDC highlights disease transmission models because they can estimate how infections spread under different assumptions (for example, changes in testing coverage, treatment uptake, partner services, vaccination, harm reduction, or outbreak response). Alongside this, economic models, including cost-effectiveness analyses, are emphasized because they help quantify tradeoffs between intervention costs and expected health benefits, such as infections averted, improved quality of life, or reduced downstream medical spending. The overall goal is to improve prevention effectiveness, meaning the CDC wants models that can meaningfully support decision-making rather than purely academic exercises.
This was published as a discretionary funding opportunity using a cooperative agreement mechanism, which usually implies substantial involvement from the funding agency during the project period. Rather than simply funding an independent research project, a cooperative agreement typically expects collaboration with CDC staff, alignment with CDC priorities, and iterative communication around methods, assumptions, and deliverables. The opportunity was open to a broad range of applicants (listed as unrestricted eligibility), subject to any additional eligibility details that may have appeared in the full announcement.
Administratively, the opportunity was created on January 28, 2019, with an original closing date of April 14, 2019, and applications were required to be submitted electronically by 11:59 p.m. Eastern Time on the due date. The agency anticipated making approximately three awards. The notice lists an award ceiling of 0, which commonly indicates that a fixed cap was not specified in the summary field and that the actual funding levels would be detailed elsewhere in the full announcement or depend on available appropriations and CDC decisions.
In summary, this grant opportunity was designed to expand the CDCs and jurisdictions ability to use credible modeling to evaluate prevention strategies across HIV, hepatitis, STDs, and TB. By supporting the development and application of transmission and economic models, the CDC aimed to help state and local partners plan, prioritize, and justify interventions based on projected public health impact and value for money, ultimately improving the effectiveness of prevention programs and guiding resource allocation.Apply for CDC RFA PS19 1905
- The Department of Health and Human Services, Centers for Disease Control - NCHHSTP in the health sector is offering a public funding opportunity titled "Economic Modeling for HIV/AIDS, Viral Hepatitis, STD, and TB" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.084.
- This funding opportunity was created on Jan 28, 2019.
- Applicants must submit their applications by Apr 14, 2019 Electronically submitted applications must be submitted no later than 1159 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 3 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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