Opportunity Information: Apply for RFA AG 25 012
The Nathan Shock Centers of Excellence in Basic Biology of Aging funding opportunity (RFA-AG-25-012) is a National Institutes of Health (NIH) grant program run through the National Institute on Aging (NIA) that supports center-based infrastructure for basic research on the biology of aging. It uses the P30 Center Grant mechanism and is explicitly designated as "Clinical Trial Not Allowed," meaning the supported work is intended to strengthen foundational, non-clinical research capacity rather than conduct clinical trials. The overall purpose is to fund coordinated centers that provide scientific leadership, training opportunities, shared research resources, and outreach activities that collectively expand and spread knowledge aligned with the NIA Division of Aging Biology.
The program is designed around building and sustaining a hub that can serve a broader research community. Rather than funding a single research project, the center structure typically emphasizes organized activities such as administrative leadership and governance, career development and training for investigators working in aging biology, and research support services that make basic aging research more efficient and higher impact. The emphasis on dissemination and outreach signals that awardees are expected to actively share expertise, methods, and resources, helping researchers beyond the immediate institution benefit from the center's capabilities and advancing the field nationally.
Eligibility is broad across U.S.-based entities, reflecting NIH's standard approach for many center programs. Eligible applicants include state, county, and local governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; Native American tribal organizations that are not federally recognized; public housing/Indian housing authorities; nonprofits with and without 501(c)(3) status (outside of higher education); for-profit organizations (other than small businesses); small businesses; and other domestic organizations. The opportunity also calls out additional eligible categories such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, and eligible federal agencies.
At the same time, the solicitation is clear about restrictions related to foreign participation. Non-domestic (non-U.S.) entities are not eligible to apply, non-domestic components of U.S. organizations are not eligible to apply, and foreign components (as NIH defines them in the NIH Grants Policy Statement) are not allowed. In practice, that means the center's applicant organization and the supported components must be domestic, and the funded activities must be carried out without a foreign component as part of the award structure.
From an administrative and budgeting standpoint, this is a discretionary grant in the health category (CFDA 93.866) under the NIH. The listed award ceiling is $1,100,000, indicating the maximum budget level expected for an individual award under this announcement. The original application due date is June 14, 2024, and the notice was created March 18, 2024. While the expected number of awards is not specified in the provided data, the structure and ceiling indicate a competitive, center-level investment intended to support robust shared resources and coordination in basic aging biology.
In short, this NOFO funds U.S.-based institutions and organizations to run Nathan Shock Centers of Excellence that strengthen the national infrastructure for basic biology of aging research through leadership, training, shared resources, and outreach, with an explicit prohibition on clinical trials and on foreign components.Apply for RFA AG 25 012
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Nathan Shock Centers of Excellence in Basic Biology of Aging (P30 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.866.
- This funding opportunity was created on 2024-03-18.
- Applicants must submit their applications by 2024-06-14. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $1,100,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQs)
What is the Nathan Shock Centers of Excellence in Basic Biology of Aging funding opportunity?
It is an NIH funding opportunity (RFA-AG-25-012) administered by the National Institute on Aging (NIA) to support center-based infrastructure for basic research on the biology of aging. The program funds coordinated centers (Nathan Shock Centers of Excellence) designed to strengthen and expand foundational research capacity in aging biology.
Which NIH Institute runs this program?
The program is run through the National Institute on Aging (NIA), which is part of the National Institutes of Health (NIH).
What is the primary purpose of this funding?
The purpose is to fund coordinated centers that provide scientific leadership, training opportunities, shared research resources, and outreach activities that expand and spread knowledge aligned with the NIA Division of Aging Biology. The focus is on strengthening national infrastructure for basic biology of aging research rather than funding a single stand-alone research project.
What grant mechanism does this opportunity use?
This opportunity uses the P30 Center Grant mechanism, which is intended to support center-based infrastructure and coordinated activities.
Are clinical trials allowed under this funding opportunity?
No. The opportunity is explicitly designated as "Clinical Trial Not Allowed," meaning the supported work is intended to strengthen foundational, non-clinical research capacity rather than conduct clinical trials.
Is this funding meant for a single research project or a research center?
It is meant for a research center. The center structure emphasizes organized, coordinated activities (such as administration, training, shared resources, and outreach) that serve a broader research community, rather than funding a single discrete research project.
What kinds of activities are centers expected to support?
Based on the opportunity description, centers typically emphasize coordinated activities such as administrative leadership and governance, career development and training for investigators working in aging biology, research support services and shared resources, and dissemination/outreach efforts to share expertise, methods, and resources.
What is meant by "center-based infrastructure" in this program?
It refers to the coordinated structure, shared resources, and organized support services that make basic aging research more efficient and higher impact. This includes activities that help multiple researchers and projects, such as shared scientific resources, training, leadership, and outreach.
Who is the intended beneficiary of the center's resources and services?
The center is designed to serve a broader research community, not only the immediate institution. The emphasis on dissemination and outreach indicates awardees are expected to share expertise, methods, and resources so researchers beyond the host institution can benefit.
What areas of research does this program align with?
The program is aligned with the NIA Division of Aging Biology and supports basic research on the biology of aging.
Who is eligible to apply?
Eligibility is broad across U.S.-based entities. Eligible applicants include state, county, and local governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; non-federally recognized Native American tribal organizations; public housing/Indian housing authorities; nonprofits with and without 501(c)(3) status (outside of higher education); for-profit organizations (other than small businesses); small businesses; and other domestic organizations.
Are any specific institution types explicitly called out as eligible?
Yes. The opportunity calls out additional eligible categories such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, and eligible federal agencies.
Can non-U.S. (foreign) organizations apply?
No. Non-domestic (non-U.S.) entities are not eligible to apply under this solicitation.
Can a U.S. organization apply if it has a non-U.S. component involved in the project?
No. The solicitation states that non-domestic components of U.S. organizations are not eligible to apply, and foreign components (as defined by NIH) are not allowed. In practice, the applicant organization and supported components must be domestic, and funded activities must be carried out without a foreign component as part of the award structure.
What is the award ceiling (maximum expected budget) for this opportunity?
The listed award ceiling is $1,100,000, indicating the maximum budget level expected for an individual award under this announcement.
What is the CFDA number and category for this opportunity?
The opportunity is listed under CFDA 93.866 and is categorized as a discretionary grant in the health category under NIH.
When is the application due?
The original application due date provided is June 14, 2024.
When was this notice created?
The notice was created on March 18, 2024.
How many awards does NIH expect to make under this opportunity?
The expected number of awards is not specified in the provided information.
What does the emphasis on dissemination and outreach imply for awardees?
It implies that awardees are expected to actively share expertise, methods, and resources. The goal is to help researchers beyond the immediate institution benefit from the center's capabilities and to advance the field more broadly.
What is the overall role of a Nathan Shock Center under this program?
The center functions as a coordinated hub that provides scientific leadership, training, shared research resources, and outreach to expand and spread knowledge in basic biology of aging and strengthen national research infrastructure in this area.
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