Specialized Alcohol Research Centers (P50 Clinical trial Optional) | RFA AA 22 001

Opportunity Information: Apply for RFA AA 22 001

The Specialized Alcohol Research Centers (P50 Clinical Trial Optional) funding opportunity (RFA-AA-22-001) is a discretionary NIH grant from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) that supports the creation or continuation of highly integrated, interdisciplinary research centers focused on alcohol-related science and public health needs. Using the P50 specialized center mechanism, the program is designed to fund coordinated teams rather than single-project efforts, with the expectation that the combined work will produce a broader impact than individual grants could achieve on their own. Clinical trials are optional under this announcement, meaning applicants may propose clinical trials when scientifically justified, but they are not required to do so.

The central aim of the NIAAA Alcohol Research Center program is to provide leadership in conducting and fostering collaborative research across a wide range of topics aligned with NIAAA's mission. Research areas can include the nature and underlying causes of alcohol use disorder (AUD), its etiology and progression, genetic and biological contributors, improved diagnosis, development and testing of treatment approaches, and prevention strategies. The FOA also explicitly emphasizes alcohol-related end organ diseases and the biomedical, psychosocial, and economic consequences of alcohol misuse. Importantly, the scope spans the entire lifespan and encourages attention to racial and ethnic groups as well as other health disparity populations, reflecting NIAAA's interest in research that addresses unequal burdens of alcohol-related harm and differences in access to effective prevention and care.

Beyond producing scientific findings, these centers are expected to serve as regional or national resources. That role includes helping to develop or refine research methods, technologies, and innovative approaches that can accelerate progress in alcohol research more broadly. In practical terms, the program is aimed at building sustainable, goal-directed research ecosystems that can support new tools, shared infrastructure, cross-disciplinary training and collaboration, and the rapid translation of discoveries into improved understanding, prevention, and treatment of alcohol-related problems.

Eligibility is broad and includes many types of U.S.-based organizations and government entities. Eligible applicants listed for this FOA include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; Native American tribal organizations that are not federally recognized tribal governments; public housing authorities and Indian housing authorities; nonprofits with or without 501(c)(3) status (other than institutions of higher education); for-profit organizations (other than small businesses); and small businesses. The announcement also calls out additional eligible applicant categories such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISI), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, tribal governments other than federally recognized entities, and U.S. territories or possessions.

Foreign eligibility is limited in a way that is typical for NIH center programs. Non-domestic (non-U.S.) entities and non-domestic foreign institutions are not eligible to apply as the applicant organization, and non-domestic components of U.S. organizations are not eligible to apply. However, foreign components are allowed when they meet NIH definitions and policies in the NIH Grants Policy Statement, which can enable specific international collaborations or activities when they are well-justified and add unique scientific value.

Key administrative details included in the source data are that this opportunity falls under CFDA 93.273 and was created on April 14, 2022, with an original closing date of November 15, 2022. The listed award ceiling is $1,150,000. The announcement is positioned as a specialized center grant, indicating NIAAA is looking for strong scientific leadership, a coherent and synergistic research agenda, and the ability to support collaborative, methodologically advanced work that meaningfully advances the field of alcohol research while also serving broader scientific and public health communities.

• The National Institutes of Health in the health sector is offering a public funding opportunity titled "Specialized Alcohol Research Centers (P50 Clinical trial Optional)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273.
• This funding opportunity was created on 2022-04-14.
• Applicants must submit their applications by 2022-11-15. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Each selected applicant is eligible to receive up to $1,150,000.00 in funding.
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

Apply for RFA AA 22 001

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