Opportunity Information: Apply for 72067418FYI00002
USAID/South Africa's Preventing HIV/AIDS in Vulnerable Populations (PHVP) activity for 2018 to 2023 is a large-scale public health initiative designed to help South Africa accelerate and sustain HIV epidemic control. The program focuses on delivering high-impact HIV prevention, care, and support services in ways that directly reduce new infections while also strengthening health and social outcomes for people and communities facing heightened HIV risk and vulnerability. It is structured as a Cooperative Agreement, meaning the U.S. government expects to play an active partnership role during implementation rather than simply issuing a grant and stepping back.
The activity is organized around three headline objectives that reflect both biomedical and social drivers of HIV. First, it aims to improve the health and wellbeing of orphans and vulnerable children (OVC), adolescents, and youth who are living with HIV, affected by HIV in their households, or otherwise vulnerable to HIV. Second, it seeks to prevent new HIV infections among priority populations, with specific attention to groups known to experience disproportionate risk. Third, it works to scale up violence prevention interventions, recognizing that gender-based violence and other forms of violence can increase HIV risk, disrupt schooling and social stability, and reduce access to prevention and treatment services.
A defining feature of PHVP is its emphasis on evidence-based interventions that have demonstrated impact. On the OVC and youth side, this typically means layered packages of services that address both immediate health needs and the broader conditions that shape vulnerability, such as household instability, poverty-related stressors, and barriers to consistent care. On the prevention side, it prioritizes approaches that reduce risk among adolescent girls and young women (AGYW), including those who have experienced violence, and it also includes work with migrant and mobile populations in selected sub-districts, reflecting the reality that mobility can interrupt care, weaken community support, and increase exposure to risk.
Implementation is divided into four core components that together create a prevention-to-care continuum while also tackling structural issues. Component 1 focuses on orphans, vulnerable children, adolescents, and youth, aiming to strengthen wellbeing and link individuals and families to appropriate health and social services. Component 2 concentrates on school-based HIV prevention and gender-based violence (GBV) prevention, using the school setting to reach adolescents with prevention education and protective interventions, and to reduce violence-related risks that can undermine health and learning outcomes. Component 3 expands into community-based violence prevention and linkages to response, pairing prevention efforts with pathways to services for survivors, which helps ensure that violence prevention is not only educational but also connected to real support and protection mechanisms. Component 4 targets prevention of new HIV infections among priority populations, aligning outreach and prevention services with those groups and localities where incidence and vulnerability are highest.
PHVP is positioned as a continuation and scale-up of prior work rather than a standalone effort. It explicitly builds on investments and results achieved by the Government of South Africa (GoSA) and USAID-supported HIV prevention, OVC, and DREAMS programming, and it is designed to leverage other USAID and development partner activities already underway. This approach is meant to avoid duplication, strengthen coordination, and push proven models further, especially in areas where coverage gaps remain or where local conditions require more tailored approaches.
The activity also aligns with South Africa's National Strategic Plan (NSP) 2017 to 2022, connecting its programming to nationally defined goals. In particular, it supports NSP Goal 1 by accelerating prevention to reduce new HIV and TB infections and sexually transmitted infections, supports Goal 3 by reaching key and vulnerable populations with customized interventions, and supports Goal 4 by addressing the underlying social and structural drivers of HIV, TB, and STIs through an integrated, multi-sectoral approach. In practical terms, this framing underscores that epidemic control depends not only on clinical services, but also on safer environments, reduced violence, stable family and community support, and targeted services that reflect real patterns of risk.
From a funding and administrative standpoint, the opportunity was issued by USAID/Pretoria under Funding Opportunity Number 72067418FYI00002. It falls under the Health funding activity category and is associated with CFDA 98.001. The opportunity listed an award ceiling of $150,000,000 and anticipated up to eight awards, indicating a sizable and multi-award program structure intended to support implementation at scale through multiple partners. The posting date was October 27, 2017, with an original closing date of November 30, 2017, and eligibility was listed broadly as "Others," with further clarification expected in the full eligibility text of the original announcement.Apply for 72067418FYI00002
- The Agency for International Development, South Africa USAID-Pretoria in the health sector is offering a public funding opportunity titled "Preventing HIV/AIDS in Vulnerable Populations" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 98.001.
- This funding opportunity was created on Oct 27, 2017.
- Applicants must submit their applications by Nov 30, 2017. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $150,000,000.00 in funding.
- The number of recipients for this funding is limited to 8 candidate(s).
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
[Watch] Creating a grant proposal using the step-by-step wizard inside the applicant portal:
Frequently Asked Questions (FAQs): USAID/South Africa Preventing HIV/AIDS in Vulnerable Populations (PHVP)
1) What is the PHVP activity?
Preventing HIV/AIDS in Vulnerable Populations (PHVP) is a USAID/South Africa public health activity (2018 to 2023) designed to help South Africa accelerate and sustain HIV epidemic control by delivering high-impact HIV prevention, care, and support services to people and communities facing heightened HIV risk and vulnerability.
2) What is the main purpose of PHVP?
The purpose is to directly reduce new HIV infections while also strengthening health and social outcomes for vulnerable individuals and communities, including those affected by HIV, those living with HIV, and populations at elevated risk.
3) What type of funding mechanism is PHVP using?
PHVP is structured as a Cooperative Agreement. This means the U.S. government expects to play an active partnership role during implementation rather than only issuing funding with minimal involvement.
4) Who is issuing this opportunity?
The opportunity was issued by USAID/Pretoria (USAID/South Africa).
5) What are the headline objectives of PHVP?
PHVP is organized around three headline objectives:
- Improve the health and wellbeing of orphans and vulnerable children (OVC), adolescents, and youth who are living with HIV, affected by HIV, or otherwise vulnerable to HIV.
- Prevent new HIV infections among priority populations, with particular attention to groups experiencing disproportionate risk.
- Scale up violence prevention interventions, recognizing the link between violence (including gender-based violence) and increased HIV risk and worse social outcomes.
6) What populations does PHVP prioritize?
Based on the opportunity description, PHVP prioritizes:
- Orphans and vulnerable children (OVC)
- Adolescents and youth
- Adolescent girls and young women (AGYW), including those who have experienced violence
- Migrant and mobile populations in selected sub-districts
- Other priority populations at heightened risk and vulnerability (as described in the opportunity)
7) Why does PHVP include a focus on violence prevention?
The activity recognizes that gender-based violence and other forms of violence can increase HIV risk, disrupt schooling and social stability, and reduce access to prevention and treatment services. PHVP includes interventions intended to reduce violence-related risks and strengthen linkages to support services.
8) What does PHVP mean by "evidence-based interventions"?
PHVP emphasizes evidence-based interventions that have demonstrated impact. In practice, this means using approaches with a track record of measurable results, including layered packages of services for OVC and youth and targeted prevention strategies for populations at higher risk.
9) What kinds of services are included for OVC, adolescents, and youth?
The opportunity describes layered packages of services that address both immediate health needs and broader conditions shaping vulnerability, such as household instability, poverty-related stressors, and barriers to consistent care, along with linkages to appropriate health and social services.
10) What prevention approaches are emphasized for AGYW?
On the prevention side, PHVP prioritizes approaches that reduce risk among adolescent girls and young women (AGYW), including those who have experienced violence, reflecting the interplay between violence, vulnerability, and HIV risk.
11) Why are migrant and mobile populations included in PHVP?
The activity includes work with migrant and mobile populations in selected sub-districts because mobility can interrupt care, weaken community support, and increase exposure to risk, all of which can elevate HIV vulnerability.
12) How is PHVP structured for implementation?
Implementation is divided into four core components intended to create a prevention-to-care continuum and address structural issues that contribute to HIV risk and vulnerability.
13) What is Component 1 focused on?
Component 1 focuses on orphans, vulnerable children, adolescents, and youth, aiming to strengthen wellbeing and link individuals and families to appropriate health and social services.
14) What is Component 2 focused on?
Component 2 concentrates on school-based HIV prevention and gender-based violence (GBV) prevention, using the school setting to reach adolescents with prevention education and protective interventions and to reduce violence-related risks that can undermine health and learning outcomes.
15) What is Component 3 focused on?
Component 3 expands into community-based violence prevention and linkages to response, pairing prevention efforts with pathways to services for survivors so prevention is connected to real support and protection mechanisms.
16) What is Component 4 focused on?
Component 4 targets prevention of new HIV infections among priority populations, aligning outreach and prevention services with groups and localities where incidence and vulnerability are highest.
17) Does PHVP build on previous programs?
Yes. PHVP is positioned as a continuation and scale-up of prior work. It builds on investments and results achieved by the Government of South Africa (GoSA) and USAID-supported HIV prevention, OVC, and DREAMS programming.
18) How does PHVP avoid duplication with other efforts?
The activity is designed to leverage other USAID and development partner activities already underway. This approach is intended to avoid duplication, strengthen coordination, and scale proven models, especially where coverage gaps remain or where local conditions require tailored approaches.
19) How does PHVP align with South Africa's National Strategic Plan (NSP) 2017 to 2022?
PHVP aligns with the NSP 2017 to 2022 by connecting programming to nationally defined goals. Specifically, it supports NSP Goal 1 (accelerating prevention to reduce new HIV and TB infections and STIs), Goal 3 (reaching key and vulnerable populations with customized interventions), and Goal 4 (addressing underlying social and structural drivers through an integrated, multi-sectoral approach).
20) What is the Funding Opportunity Number (FON) for this announcement?
The Funding Opportunity Number is 72067418FYI00002.
21) What is the funding activity category?
The opportunity falls under the Health funding activity category.
22) What CFDA number is associated with this opportunity?
The opportunity is associated with CFDA 98.001.
23) What is the award ceiling listed for this opportunity?
The opportunity listed an award ceiling of $150,000,000.
24) How many awards were anticipated?
USAID anticipated up to eight awards, indicating a multi-award structure intended to support implementation at scale through multiple partners.
25) When was the opportunity posted and when did it close?
The posting date was October 27, 2017, and the original closing date was November 30, 2017.
26) Who was eligible to apply?
Eligibility was listed broadly as "Others," with further clarification expected in the full eligibility text of the original announcement.
27) What does the multi-award design suggest about implementation?
The anticipated multiple awards (up to eight) and the large award ceiling suggest a sizable program intended to operate at scale and potentially across multiple localities and priority populations, supported by multiple implementing partners.
28) What is meant by a "prevention-to-care continuum" in this activity?
In the PHVP description, the prevention-to-care continuum refers to an approach that connects prevention efforts (such as school- and community-based prevention and targeted services for priority groups) with linkages to care, support, and response services, including health and social services and survivor support pathways.
29) What role do schools play in PHVP?
Schools are used as a key platform for reaching adolescents with HIV prevention and GBV prevention education and protective interventions, helping reduce violence-related risks that can undermine both health and learning outcomes.
30) How does PHVP address structural and social drivers of HIV?
PHVP addresses structural and social drivers through integrated approaches that include violence prevention, strengthening linkages to health and social services, and multi-sectoral programming aligned with national strategic priorities.
Browse more opportunities from the same category: Health
Next opportunity: Rehabilitation Research and Training Center (RRTC) on Disability in Rural Communities
Previous opportunity: Limited Competition for Continuation of the Prospective Study of Chronic Kidney Disease in Children Data Coordinating Center (U24)
Applicant Portal:
Are you interested in learning about about how to apply for this government funding opportunity? You can create a free applicant account and receive instant access to our applicant portal that many business owners like you have benefited from.
Apply for 72067418FYI00002
Applicants also applied for:
Applicants who have applied for this opportunity (72067418FYI00002) also looked into and applied for these:
| Funding Opportunity |
|---|
| FY 2018 Opioid State Targeted Response Technical Assistance (Short Title: STR TA) Apply for TI 18 004 Funding Number: TI 18 004 Agency: Department of Health and Human Services, Substance Abuse and Mental Health Services Adminis Category: Health Funding Amount: $12,000,000 |
| Center of Excellence for Research on Complementary and Integrative Health (P01 Clinical Trial Optional) Apply for PAR 18 113 Funding Number: PAR 18 113 Agency: Department of Health and Human Services, National Institutes of Health Category: Health Funding Amount: $1,250,000 |
| NIDCR Award for Sustaining Outstanding Achievement in Research (SOAR) (R35)- Clinical Trial Not Allowed Apply for RFA DE 18 011 Funding Number: RFA DE 18 011 Agency: Department of Health and Human Services, National Institutes of Health Category: Health Funding Amount: $650,000 |
| Resilient and Responsive Health Systems (RRHS) Initiative – South Sudan Apply for HRSA 18 098 Funding Number: HRSA 18 098 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| Thalassemia Program Apply for HRSA 18 079 Funding Number: HRSA 18 079 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| National Maternal and Child Health Data Resource Initiative Apply for HRSA 18 084 Funding Number: HRSA 18 084 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| Emergency Medical Services for Children State Partnership Program Apply for HRSA 18 063 Funding Number: HRSA 18 063 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: $130,000 |
| R40 Maternal and Child Health Field-Initiated Innovative Research Studies (FIRST) Program Apply for HRSA 18 071 Funding Number: HRSA 18 071 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| R40 Maternal and Child Health (MCH) Secondary Data Analysis Research (SDAR) Program Apply for HRSA 18 072 Funding Number: HRSA 18 072 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| Advancing Systems of Services for Children and Youth with Special Health Care Needs Apply for HRSA 18 069 Funding Number: HRSA 18 069 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| FY18 Office of Population Affairs Research Grant Priorities Apply for PA FPR 18 001 Funding Number: PA FPR 18 001 Agency: Department of Health and Human Services, Office of the Assistant Secretary for Health Category: Health Funding Amount: $400,000 |
| Title X Family Planning Clinical Training Cooperative Agreement Apply for PA FPT 18 001 Funding Number: PA FPT 18 001 Agency: Department of Health and Human Services, Office of the Assistant Secretary for Health Category: Health Funding Amount: $800,000 |
| Ryan White HIV/AIDS Program Part F Community Based Dental Partnership Program Apply for HRSA 18 046 Funding Number: HRSA 18 046 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| Ryan White HIV/AIDS Program Part F Dental Reimbursement Program Apply for HRSA 18 052 Funding Number: HRSA 18 052 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| FY18 Office of Population Affairs Research Grant Priorities Apply for PA FPR 18 002 Funding Number: PA FPR 18 002 Agency: Department of Health and Human Services, Office of the Assistant Secretary for Health Category: Health Funding Amount: $400,000 |
| TB Platforms for Sustainable Detection, Care and Treatment Activity Apply for 72049218RFA00001 Funding Number: 72049218RFA00001 Agency: Agency for International Development, Philippines USAID-Manila Category: Health Funding Amount: $20,000,000 |
| Nurse Education, Practice, Quality and Retention (NEPQR) – Registered Nurses in Primary Care (RNPC) Training Program Apply for HRSA 18 012 Funding Number: HRSA 18 012 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| Preventive Medicine Residency Program Apply for HRSA 18 008 Funding Number: HRSA 18 008 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| Improving Student Health and Academic Achievement through Nutrition, Physical Activity and the Management of Chronic Conditions in Schools Apply for CDC RFA DP18 1801 Funding Number: CDC RFA DP18 1801 Agency: Department of Health and Human Services, Centers for Disease Control - NCCDPHP Category: Health Funding Amount: $500,000 |
| Primary Care Training and Enhancement: Training Primary Care Champions Apply for HRSA 18 013 Funding Number: HRSA 18 013 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
Grant application guides and resources
It is always free to apply for government grants. However the process may be very complex depending on the funding opportunity you are applying for. Let us help you!
Apply for Grants
Inside Our Applicants Portal
Access Applicants Portal
- Grants Repository - Access current and historic funding opportunities with ease. Thousands of funding opportunities are published every week. We can help you sort through the database and find the eligible ones to apply for.
- Applicant Video Guides - The grant application process can be challenging to follow. We can help you with intuitive video guides to speed up the process and eliminate errors in submissions.
- Grant Proposal Wizard - We have developed a network of private funding organizations and investors across the United States. We can reach out and submit your proposal to these contacts to maximize your chances of getting the funding you need.
Premium leads for funding administrators, grant writers, and loan issuers
Thousands of people visit our website for their funding needs every day. When a user creates a grant proposal and files for submission, we pass the information on to funding administrators, grant writers, and government loan issuers.
If you manage government grant programs, provide grant writing services, or issue personal or government loans, we can help you reach your audience.
Learn More
Request more information:
Would you like to learn more about this funding opportunity, similar opportunities to "72067418FYI00002", eligibility, application service, and/or application tips? Submit an inquiry below:
Don't forget to subscribe to our grant alerts mailing list to receive weekly alerts on new and updated grant funding opportunities like this one in your email.