Opportunity Information: Apply for 72067418FYI00002
USAID/South Africa's Preventing HIV/AIDS in Vulnerable Populations (PHVP) activity for 2018 to 2023 is a large-scale public health initiative designed to help South Africa accelerate and sustain HIV epidemic control. The program focuses on delivering high-impact HIV prevention, care, and support services in ways that directly reduce new infections while also strengthening health and social outcomes for people and communities facing heightened HIV risk and vulnerability. It is structured as a Cooperative Agreement, meaning the U.S. government expects to play an active partnership role during implementation rather than simply issuing a grant and stepping back.
The activity is organized around three headline objectives that reflect both biomedical and social drivers of HIV. First, it aims to improve the health and wellbeing of orphans and vulnerable children (OVC), adolescents, and youth who are living with HIV, affected by HIV in their households, or otherwise vulnerable to HIV. Second, it seeks to prevent new HIV infections among priority populations, with specific attention to groups known to experience disproportionate risk. Third, it works to scale up violence prevention interventions, recognizing that gender-based violence and other forms of violence can increase HIV risk, disrupt schooling and social stability, and reduce access to prevention and treatment services.
A defining feature of PHVP is its emphasis on evidence-based interventions that have demonstrated impact. On the OVC and youth side, this typically means layered packages of services that address both immediate health needs and the broader conditions that shape vulnerability, such as household instability, poverty-related stressors, and barriers to consistent care. On the prevention side, it prioritizes approaches that reduce risk among adolescent girls and young women (AGYW), including those who have experienced violence, and it also includes work with migrant and mobile populations in selected sub-districts, reflecting the reality that mobility can interrupt care, weaken community support, and increase exposure to risk.
Implementation is divided into four core components that together create a prevention-to-care continuum while also tackling structural issues. Component 1 focuses on orphans, vulnerable children, adolescents, and youth, aiming to strengthen wellbeing and link individuals and families to appropriate health and social services. Component 2 concentrates on school-based HIV prevention and gender-based violence (GBV) prevention, using the school setting to reach adolescents with prevention education and protective interventions, and to reduce violence-related risks that can undermine health and learning outcomes. Component 3 expands into community-based violence prevention and linkages to response, pairing prevention efforts with pathways to services for survivors, which helps ensure that violence prevention is not only educational but also connected to real support and protection mechanisms. Component 4 targets prevention of new HIV infections among priority populations, aligning outreach and prevention services with those groups and localities where incidence and vulnerability are highest.
PHVP is positioned as a continuation and scale-up of prior work rather than a standalone effort. It explicitly builds on investments and results achieved by the Government of South Africa (GoSA) and USAID-supported HIV prevention, OVC, and DREAMS programming, and it is designed to leverage other USAID and development partner activities already underway. This approach is meant to avoid duplication, strengthen coordination, and push proven models further, especially in areas where coverage gaps remain or where local conditions require more tailored approaches.
The activity also aligns with South Africa's National Strategic Plan (NSP) 2017 to 2022, connecting its programming to nationally defined goals. In particular, it supports NSP Goal 1 by accelerating prevention to reduce new HIV and TB infections and sexually transmitted infections, supports Goal 3 by reaching key and vulnerable populations with customized interventions, and supports Goal 4 by addressing the underlying social and structural drivers of HIV, TB, and STIs through an integrated, multi-sectoral approach. In practical terms, this framing underscores that epidemic control depends not only on clinical services, but also on safer environments, reduced violence, stable family and community support, and targeted services that reflect real patterns of risk.
From a funding and administrative standpoint, the opportunity was issued by USAID/Pretoria under Funding Opportunity Number 72067418FYI00002. It falls under the Health funding activity category and is associated with CFDA 98.001. The opportunity listed an award ceiling of $150,000,000 and anticipated up to eight awards, indicating a sizable and multi-award program structure intended to support implementation at scale through multiple partners. The posting date was October 27, 2017, with an original closing date of November 30, 2017, and eligibility was listed broadly as "Others," with further clarification expected in the full eligibility text of the original announcement.Apply for 72067418FYI00002
- The Agency for International Development, South Africa USAID-Pretoria in the health sector is offering a public funding opportunity titled "Preventing HIV/AIDS in Vulnerable Populations" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 98.001.
- This funding opportunity was created on Oct 27, 2017.
- Applicants must submit their applications by Nov 30, 2017. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $150,000,000.00 in funding.
- The number of recipients for this funding is limited to 8 candidate(s).
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
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